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AUTHOR(S): Cristina Popa, Mioara Petrus, Ana-Maria Bratu
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TITLE Laser Photoacoustic Spectroscopy (LPAS) in the Context of Biomedicine |
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ABSTRACT Helicobacter pylori (HP) is a bacterium commonly found in the stomach, and its detection is crucial in clinical practice due to its association with peptic ulcers, chronic stomach inflammation, and stomach cancer. HP possesses an enzyme called urease, which naturally hydrolyzes urea into ammonium carbonate. In this research study, the concentration of ammonia in the breath of individuals with HP was measured using the photoacoustic spectroscopy method. The goal was to compare the levels of ammonia in the breath of individuals with HP to those of healthy individuals. The results of the study revealed that the concentration of ammonia was elevated by 498 parts per billion (ppb) in individuals with HP compared to the breath of healthy individuals. This finding suggests a potential correlation between HP infection and increased levels of ammonia in breath samples. The measurement of ammonia levels using photoacoustic spectroscopy provides valuable insights into the metabolic processes and bacterial activity associated with HP infection. Further research is warranted to elucidate the mechanisms underlying this observed increase in ammonia concentration and its clinical implications for the diagnosis and management of HP-related conditions. |
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KEYWORDS human respiration, photoacoustics, ammonia, helicobacter pylori, breath test |
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Cite this paper Cristina Popa, Mioara Petrus, Ana-Maria Bratu. (2024) Laser Photoacoustic Spectroscopy (LPAS) in the Context of Biomedicine. International Journal of Biology and Biomedicine, 9, 7-10 |
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