A Data Driven Approach to Predicting Hemodynamic Factors of Coronary Stenosis Severity

AUTHOR(S):

Duc Minh Tran, Minh Tuan Nguyen, Sang-Wook Lee

TITLE

A Data Driven Approach to Predicting Hemodynamic Factors of Coronary Stenosis Severity

ABSTRACT

In this study, a data driven approach to predicting hemodynamics based diagnostic factors for ischemic severity of stenotic lesion of coronary by a machine learning technique was proposed. For a training dataset, we generated total 1,116 coronary vessel models with various geometric features of a stenosis and conducted 3D-0D coupled blood flow dynamics simulations. We employed a fully connected deep neural network model with four hidden layers and a sigmoidal activation function. This novel approach produced a promising outcome for near-real time assessment of coronary lesion severity with reasonable accuracy.

KEYWORDS

Coronary circulation, Stenosis severity, Computational fluid dynamics, Machine learning, Hemodynamic factor, Geometric features, Physiological index

REFERENCES

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Cite this paper

Duc Minh Tran, Minh Tuan Nguyen, Sang-Wook Lee. (2018) A Data Driven Approach to Predicting Hemodynamic Factors of Coronary Stenosis Severity. International Journal of Biology and Biomedicine, 3, 30-31