Electrophysical Modelling of Axon in Neuron and Its Analysis

AUTHOR(S):

Yumi Takizawa, Atsushi Fukasawa

KEYWORDS

Electrophysical modelling of axon, Myelination and unmyelination in axon, Velocity and bandwidth, Attenuation, Phase rotation

ABSTRACT

Electrophysical modelling of axon and its analysis are given based on voltage equilibrium and current continuity conditions. Inductance L and capacity C per unit length are obtained for lossless axon. Attenuation, phase rotation, and phase (signal) velocity are given for axon with loss. It is then presented that higher velocity and wideband signal transmission are realized by reduction of C and L by myelination and large cross section of axons. Loss and phase rotation per unit length are also obtained for axon with serial resistance r and parallel conductance g. Long distance transmission is found available by reduction of serial resistance r and parallel conductance g by voltage dependent Na+ channels distributed at unmyelinated parts of axons.

Cite this paper

Yumi Takizawa, Atsushi Fukasawa. (2016) Electrophysical Modelling of Axon in Neuron and Its Analysis. International Journal of Medical Physiology, 1, 8-13